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[DOI] [PMC free article] [PubMed] [Google Scholar] Uddin GM, Youngson NA, Chowdhury SS, Hagan C, Sinclair DA, Morris MJ

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One thing to consider is that because ME/CFS is a severely disabling disease, many patients are house or bedbound and are unable to visit the clinics multiple times for follow-up analyses (587)

however, T-cell receptor (TCR)-stimulated activation increases the expression of the Myc transcription factor, glutamine transporters (SLC38A1, SLC38A2), and glutaminolysis-related enzymes (GLS, GLUD1, GOT, GPT) to meet bioenergetic and biosynthetic requirements, resulting in T-cell proliferation 130,131,132,133