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The association of the variant GPX4 genotypes with the increased risk of CS in hypertensives remained statistically significant after adjusting for confounding variables such as sex, body mass index (BMI), blood pressure and antihypertensive medication use (OR=2.18, 95%CI 1.463.27, P =0.0015)

Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40