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At Dermo Direct, we are frequently asked: What supplements can I take while on isotretinoin? Are there vitamins that help with dryness or side effects? Which supplements should I avoid? As a Dermatologist I often suggest that a lot of oral supplements are not needed whilst taking isotretinoin, as gentle skin care, emollient use and sunscreen/sun protection are the key focus areas for patients taking isotretinoin but if patients are struggling with certain side effects, some of the following supplements can help

Rat inferior caval vein (ICV) ligature and BPC 157

Effects of Body Protection Compound 157 Promotes Healing : Known to support tissue repair and recovery, particularly in muscles, tendons, and ligaments

Foundation Phase Common Experiences Deeper sleep and increased dream vividness Improved morning alertness upon waking Mild water retention (2-4 lbs typical) Possible injection site redness (resolves quickly) What to Focus On Maintain consistent injection timing (before bed) Avoid eating for 2-3 hours before administration Keep a simple log of sleep quality and morning energy Week 3-4: Energy and Recovery Improvements The third and fourth weeks typically mark the transition from subtle sleep changes to functional improvements you can measure through daily activities