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Despite these advances, significant challenges continue to hinder clinical translation

Nutritional transition is the concept of demographic and socio-economic changes toward rapid alteration in dietary habits and physical activity levels, especially in low-income nations

Glutathione is a potent antioxidant that plays many roles in disease prevention and treatment

Some of the strongest candidates involved in mitochondrial import of cytosolic GSH include the dicarboxylate transporter (DIC) and the 2-oxoglutarate transporter (OGC) which act as exchangers of Pi 2 (inorganic phosphorous) and 2-oxoglutarate (2-OG 2 7 ) for cytosolic GSH