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Results NAFLD development was associated with TNF overproduction and perturbation of glutathione homeostasis in the liver Long-term HFD consumption in mice represents a well-established animal model of NAFLD
All mice were inoculated with control cells in one flank and GCLC -silenced cells in the opposite flank
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NAFLD could be considered an hepatic manifestation of metabolic syndrome, with a strong association with obesity, type 2 diabetes, hypertension, and dyslipidaemia (3)
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