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Description A solitary cigarette lies in the foreground, symbolizing temptation amidst the trio of its companions, each representing the allure of indulgence and the struggle for self-control

Further, given the known strong links between cigarette smoking and FEV1, 28 as well as with cerebrovascular disease, 1 covarying for FEV1 and Fazekas score might substantially control for the amount of smoking and hence overcontrol for the effect of interest, namely the possible impact of smoking on the cortex