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Sensation is assessed by asking patients to report when they perceive the first detectable sensation, the desire to defecate (or urgency), and maximal tolerable discomfort during rectal balloon distention, generally with a handheld syringe

It is important to note that following the cessation of treatment at week 26 and again at the end of the weaning treatment administration there was a slight increase in weight in both the cagrilintide and the liraglutide groups

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But she soon discovered that, while these patients looked more lively on the outside, many were struggling on the inside