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Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-

One such advancement involves the development of nitrogen-functionalized HAs (NHAs), which incorporate reactive nitrogen groups, such as nitro (NO 2 ), nitroso (NO), amide (CONH 2 ), and amine (NH 2 ), into the HA molecular structure [55]

To ensure that this was indeed the case, WT, REW and PGLALA anti-NIP IgG1 variants were coated directly in ELISA wells in parallel with an IgG1 variant containing the E345R/E430G/S440Y (RGY) amino acid substitutions, which is known to form solution phase hexamers 40