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According to WebMD, The more common B12 injection side effects are: Swelling at the injection site Mild dirhhea Itching Swelling in the body Low potassium (weakness, irregular heartbeat) There is a case report of an anaphylactic reaction to a B12 injection in a 55 year old women receiving cyanocobalamin, but these reactions are thought to be rare

4c, d), suggesting an improvement in anti-inflammatory capacity

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These side effects are typically very short-lived, if they occur at all, and should predictably resolve within 15 minutes of administration