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The primary treatment for ischemic stroke involves thrombolytic therapy with recombinant tissue plasminogen activator (rtPA)

Beyond the four principal RCD pathways discussed above, two additional forms, panoptosis and cuproptosis, have recently been identified

there was no change in ALT non-responders

Disruption of mitochondrial complex I and metabolic stress can also promote necroptosis, mediated by RIPK3-dependent pathways observed in Salmonella and Listeria infections (Sai et al., 2019