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Some studies also investigate DSIP indirectly in pain and chronic pain models, primarily by evaluating how sleep quality and stress modulation affect pain perception rather than through direct analgesic effects

The complex pathophysiology and the metabolic risk factors shared between type 2 diabetes, obesity, CKD and cardiovascular disease have led to the concept of a cardiovascularkidneymetabolic (CKM) syndrome

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Infectious complications of biological and small molecule targeted immunomodulatory therapies