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The majority of current evidence results from preclinical studies, highlighting the critical necessity for carefully organised human clinical trials to validate its therapeutic advantages (Culpepper, 2022)

doi: 10.1073/pnas.1804764115 Guo, Shaodong, Herzig, Volker and King, Glenn F

& Allegri, M

Together, these interlinked processes create a pro-fibrotic, pro-mutagenic microenvironment that underlies the transition from chronic liver injury to cirrhosis and HCC