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We found that, as with folate deficiency (which may effectively alter methylation reactions and deoxyribonucleotide biosynthesis), methionine loading (which maintains an efficient transmethylation pathway) promotes the occurrence of an oxidant stress-mediated prethrombotic state that is correlated with total plasma homocysteine concentration (Durand et al, 1997a

Vitamin C is important for collagen synthesis, skin repair, and brightening, while also working as an antioxidant

When highly oxidized proteins form crosslinked aggregates that are difficult to be degraded by the ubiquitinproteasome system, they are redirected to degradation by the autophagy system [107]

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