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Langton, Artificial Life, in Artificial Life: Proceedings of an Interdisciplinary Workshop on the Synthesis and Simulation of Living Systems (1989), p

The public, especially people who smoke, need to have accurate information about products relative harms, he said, and to know that while nicotine is addictive and not harmless, it is not the main cause of the chronic diseases and cause of death. Bates additionally questioned whether such a major intervention is even plausible

Covariate adjustment had non-uniform effects on the magnitude of associations, with some reports showing no effect of covariate adjustment and other studies showing a reduction in the estimate from unadjusted to adjusted models

Standard size filters (not compatible with slim cigarettes)