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Safety Concerns Therapeutic peptides are generally considered safe with low immunogenicity and a favorable adverse effect profile compared with many pharmacologic agents

Optimized Pharmacokinetics: Utilizing nasal spray formulations in research optimizes the pharmacokinetic profiles of peptides like TB500 and BPC157, enhancing the efficiency and effectiveness of their application in regenerative medicine studies

Pain relief in some instances may last longer than steroid injections

Drugs that usually cannot enter the CNS may become therapeutically beneficial by IN administration, as they bypass the BBB at significantly lower doses, with a subsequent decrease in adverse effects [9]