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The endothelium layer of our arteries produce nitric oxide, which helps relax narrowed blood vessels and increases oxygen and blood flow

Conclusion and perspective The production of oxidizing species, including ROS, can damage DNA, proteins, lipids, and carbohydrates, and even lead to cell death

Collectively, these data have identified a biological difference between children who are discordant for konzo and emphasize the role of oxidative stress in neglected motor system diseases, effectively opening new venues for research into potential disease mitigation strategies

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