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A few symptoms of B12 deficiency include: Conditions of the small intestine (Crohns disease), anaemia, fatigue, constipation, poor balance, memory loss, shortness of breath, and more

Academic consortia could run mid-sized trials, but the incentives for grant-funded investigators to study a compound with no pharma sponsor are weak

In MS research, tolerogenic peptide approaches targeting myelin basic protein have shown early promise

You should get B12 shots weekly to monthly for maintenance and IV infusions monthly to quarterly for broader wellness support, though frequency depends on deficiency severity, health goals, and your providers recommendation