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In CD, characteristic lesions at colonoscopy are deep linear ulcers (rake ulcers) with surrounding erythema and granularity and skip areas of normal-appearing mucosa between areas of involvement (Figure 15.2)

Two types of medications for ulcers and gastric reflux proton-pump inhibitors, such as omeprazole (Prilosec) and lansoprazole (Prevacid), and H2 blockers like cimetidine (Tagamet), famotidine (Pepcid), and ranitidine (Zantac) inhibit the release of stomach acid necessary to free dietary vitamin B12

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