To ensure the appropriate use of NAC to prevent liver injury from acetaminophen toxicity, a nomogram that plots acetaminophen plasma concentrations against the time of overdose was developed [63] and subsequently modified [60, 61]
Toxicology Findings Repeated-dose toxicity studies in rats, dogs, and mice for up to 6 weeks across doses from 6 mcg/kg to 20 mg/kg via various routes showed excellent tolerance
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