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In addition, oxidative stress also induces fetal programming which contributes to the development of adult-onset diseases (Luo, et al., 2006) Endothelial cells of blood vessels are damaged as early as during the first month of life of children exposed to second hand smoke and these effects can be detected during the first decade of life (Das, 2003)

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Diverse cellular functions, including the regulation of inflammatory gene expression, DNA repair, and cell proliferation, are regulated by changes in DNA methylation, covalent histone modifications, and microRNA expression patterns