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Potential neurotransmitters: As an excitatory neurotransmitter, glutathione depolarizes neurons by acting as ionotropic receptors of its own which are separate from any other excitatory amino acid receptors

Compared to that observed in cells expressing MRP1, the stimulation of GSH efflux in the presence of verapamil was still maintained with M5, half-reduced with M2, more strongly impacted with M6 and almost completely lost with M8 (Fig

It is difficult to give an exact explanation for these sensations but, like motor nerves, the sensory nerves, along with their connections in the spinal cord and brain, become hyperexcitable during withdrawal

We anticipate that the search for more specific GST inhibitors will be the main goal of future research in this field