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PBC, primary biliary cholangitis

Vitamin B12 is used to catalyze weight loss, so being B12 deficient can affect your fitness and health goals

To convert those values to molarity in the gut we assumed a gut volume of 1 liter

In preclinical models, ERR activation: Stimulates expression of genes associated with aerobic exercise adaptation Enhances mitochondrial biogenesis and oxidative respiration Increases fatty acid oxidation in skeletal and cardiac muscle Supports endurance capacity and metabolic flexibility Because of these effects, the compound has been described in the literature as an exercise mimetic a molecule that may reproduce certain biochemical signatures of physical training without the training stimulus itself