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[20] In short, the active ingredient (vitamin B) is well-known, but the specific compounded formulation is not an FDA-approved branded product

Also, pentadecapeptide BPC 157, given peripherally, could affect sphincter function through serotonin (51, 52) or dopamine (in the same dose-range that BPC 157 prevented/reversed catalepsy or stereotypy and all concomitant gastrointestinal lesions) (53-56), likely providing a particular balance between peripheral and central effects (57)

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However, under therapy-induced stress, cancer cells and non-neoplastic stromal cells mobilize survival signals that nurture the residual disease until minority drug-resistant clones emerge to lead the outgrowth of a drug-resistant tumor