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Prognostic value of glutaminase 1 in breast cancer depends on H3K27me3 expression and menopausal status

thalamus and hypothalamus: ( p = 0.05)

Stamp vertically with light pressure

Thus, two conditions are required for AG-120 efficacy against wtIDH1 tumors: 1) low Mg 2+ (to inhibit wtIDH1 activity), and 2) low nutrients (such that wtIDH1 is required for cell survival)