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Free-form phenolic activities were greater than the bound form

While the original 2002 paper in the Journal of Cosmetic Dermatology is referenced throughout current dermatology literature (including Pickart & Margolina, 2018), direct access is available through Wiley Online Library

Cytokine & Chemokine Modulation TB-500 has been shown to modulate the expression of several cytokines in laboratory models: Anti-Inflammatory Signaling In preclinical models, TB-500 has been observed to reduce the expression of pro-inflammatory mediators while promoting the activity of anti-inflammatory cytokines

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