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Ferritinophagy, a ferritin degradation pathway, depends on NCOA4 (Lin et al., 2020), a selective cargo receptor for the autophagic turnover of ferritin by lysosomes (Mancias et al., 2014)

An initial approach was the design of GST inhibitors to act as reasonably non-toxic modulatory agents, useful in situations where conventional anticancer agents are detoxified by GSTs

Bibliography Sikiric P, Rucman R, Turkovic B, Sever M, Klicek R, Radic B, et al

In this context, it is highly important to gain a better understanding of the complex and finely tuned regulatory and signaling networks functioning in plant stress response at the subcellular level