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It has less muscle wasting, much better safety profile, lower side effect profile, but people drop substantial amounts of body fat

and the interplay between the endoplasmic reticulum and actin to drive the contraction of the Drp1 protein to reduce the molecular spacing, leading to the rupture of the OMM and IMM and ultimately triggering mitochondrial fission (Giacomello et al., 2020

As B12 is essential for the production of red blood cells and proper nervous system function, its deficiency can disrupt these processes and lead to symptoms like gastrointestinal discomfort and poor appetite, which may contribute to unintended weight loss

doi: 10.1186/s12885-018-5030-1 124 PinheiroLCLPereiraRFrancelinoALGuembarovskiAFMLFugantiPEde OliveiraKBet al