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"Principles of long-term dynamics of dendritic spines." J Neurosci 28(50): 13 92-608

Increasing should be based on careful assessment of response, not impatience for faster results

Those were all discovered in, you know, plant tissues

2000 in Hormone Research showed that 21-day oral AOD-9604 (500 mcg/kg/day) reduced body weight gain by roughly 50% in obese Zucker rats with no insulin sensitivity penalty