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A growing problem Yet their use appears to be spreading rapidly

Rearrangement of (ribose-5-phosphate + xylulose-5-phosphate) to form sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate by transketolase : reversible Glyceraldehyde-3-phosphate is a glycolysis intermediate

Conventional accelerometry (step-counters etc.) measures only gross limb movements but cannot distinguish fine motor control indicative of functional arm/hand use