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86 In this model, CLP induced PMN infiltration in the peritoneal cavity, the site of infection, as well as in the lung, ultimately resulting in lung injury and death, with a concomitant decrease in endogenous GSH

The following antibodies were used for immunohistochemistry: anti-GPX4 (1:400, Abcam, ab125066), anti-4HNE (1:400, Abcam, ab46545) and anti-MPO (1:200, Dako, IS511) were employed with a secondary biotinylated antibody (Vector, MP-7401)

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