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We observed an increase in the activity of AChE in the hippocampus of diabetic rats in this study, but in our earlier study (Minaz et al., 2018), we have observed a decrease in the activity of AChE

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Based on these findings and PK/PD modeling, we doubled our dose to 25 mg b.i.d

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J Am Heart Assoc 12(11):e029298

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