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Sulfamethoxazole and trimethoprim is not indicated for prophylactic or prolonged administration in otitis media at any age

In their study [96], children suffering from the disease were randomly assigned to either a standard treatment (recommended by the WHO) or one of the three study groups receiving either 2 600 mg of reduced glutathione (GSH) or 2 50 mg of -lipoic acid or 2 100 mg of N-acetylcysteine per day