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3027046, 10.31083/FBL27046 Summary Keywords mitochondrial dysfunction, mitochondria-targeted antioxidants, muscle wasting pathways, oxidative stress, ROS, rotator cuff injury, supraspinatus atrophy Citation Pang E, Zou Y, Lu K, Li J, Chen X, Zhu Y, Wang T, Shi L and Kang H (2026) Mitochondrial ROS dyshomeostasis: a key driver of accelerated supraspinatus atrophy after rotator cuff injury