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PMID: 41534520

Nature 458:762765 Galan-Cobo A, Sitthideatphaiboon P, Qu X et al (2019) LKB1 and KEAP1/NRF2 Pathways cooperatively promote metabolic reprogramming with enhanced glutamine dependence in KRAS-mutant lung adenocarcinoma

As previously noted, MDA5 is capable of identifying dsRNA and exhibits significant structural homology with the RIG-I receptor

Although these drugs have significant effects in antitumor and other disease treatments, due to their lack of selectivity, they may also cause damage to normal cells, leading to side effects and drug resistance [474]