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Early brain injury alters the blood-brain barrier phenotype in parallel with -amyloid and cognitive changes in adulthood

The ability of GC4419 to remove superoxide anions selectively without interacting with other oxidants makes it a further intriguing SOD mimic (Aston et al., 2001), and GC4419 shows therapeutic effects in a mouse model of arthritis (Salvemini et al., 2001)