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These receptors possess intracellular domains responsible for interacting with other proteins and protein complexes, such as CARDs bound to caspase 1, or using their pyrin domain to recruit CARDs an essential stage for cytokines production and the binding of the adapter protein ASC (Yang et al., 2019)

10.1155/2017/2309034 Mediators Inflamm

However, one should not forget about the side effects of the drug, such as peripheral edema, facial flushing, pain, dizziness, palpitations, weakness, and others 98

Similarly, in B, a bidentate iron chelator L1 has a similar response, inhibiting iron-mediated hemoglobin oxidation [5]