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Interest in such applications is largely driven by their proposed mechanisms of action, including enhancement of tissue repair, modulation of inflammation, and cytoprotective effects observed in preclinical studies

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Acetyl-L-carnitine (ALCAR) is a naturally-occurring modified amino acid found in many animal-based foods and available as a dietary supplement

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Additionally, when titrating GSSG to the enzyme in the presence of limiting NADPH (relative to SmTGR concentration) and observing the resulting net single turnover reaction, there appears to be little change to the observed kinetics

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