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, Helms, C

including severe skin and liver reactions

When acetaminophen is consumed in toxic doses, the pathways leading to nontoxic metabolites are overwhelmed and the accumulation of NAPQI depletes glutathione

[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Ellul P., Maruani A., Vantalon V., Humeau E., Amestoy A., Anchordoqui A., Atzori P., Baleyte J.M., Benmansour S., Bonnot O., et al