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When supplementing with vitamin B12, there are several different forms available

2009 Aug;151(3):16775

Regardless, it is unlikely to be the only mechanism at work and additional mechanisms operating at the synaptic, cellular, and network levels might be involved in homeostatic regulation of activation of inhibitory neurons

Like with methacholine, the extra methyl side group in bethanechol results in selectivity for muscarinic vs nicotinic receptors, and contributes to resistance to metabolism by cholinesterases