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Patients Were Younger And More Symptomatic The clinical profile of patients with combined smoking differed meaningfully from that of tobacco-only smokers

Thus, the Times had run an editorial in August of 1969 announcing that as of January, 1970, the newspaper would accept cigarette ads only if they contained a warning about the hazards of smoking and a disclosure of tar-and-nicotine content

Given that two-thirds of smokers are expected to die from diseases caused by tobacco use, this is a clinically meaningful decline