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SLC25A22 induces glutamine addiction in K-ras mutated CRC (118), which accounts for 30-40% of CRCs (119)

This provides a potentially greater window of opportunity to lower the dose required to provide therapeutic benefit while sparing normal tissues from unwanted side effects

Upon successful activation against invasive pathogens, the plants two-tiered immune system, including PTI (Pattern Triggered Immunity) and ETI (Effector Triggered Immunity), spontaneously raises its tolerance as well as simultaneously reduces the damage caused to it due to various agencies of stress-derived constituents [90]