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Indeed, cell-mediated immunity requires that protein antigens be first degraded in the endocytic vesicles of APCs (eg, macrophages, dendritic cells), so that the smaller peptides can be presented on the cell surface by the major histocompatibility complex to activate proliferation of antigen-specific T cells

PMID: 36512741

While the blend combines two complementary peptide mechanisms within a single formulation, several other peptides are used by researchers to study overlapping biological pathways involved in structural tissue remodeling and cellular signaling