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Usually, children ingest raw or undercooked freshwater fish infrequently, while the proportion and frequency increase with age, particularly in males (60)

A previous report showed that activated glial cells can participate in the death of dopaminergic neurons, probably by the activation of apoptosis by cytokines like TNF-, IL-1B, IL-6 and interferon- and the subsequent production of nitric oxide (NO) by the iNOS that may diffuse toward the neurons and induce lipid peroxidation, DNA strands breaks and inhibition of mitochondrial metabolism [6,10]

Two primary factors contribute to solid stress: compressive and residual stress [111, 113,114,115]

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