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The structural modifications extend plasma half-life from approximately 1020 minutes for native IGF-1 to approximately 2030 hours for IGF-1 LR3, producing a substantially different pharmacokinetic profile than the native molecule despite identical receptor pharmacology [1]

Reported or plausible effects can include local irritation at the site of use, headache, flushing, nausea, fatigue, or dizziness

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