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Description

Tirzepatide produces weight reduction through GLP-1 and GIP receptor activation, which delays gastric emptying, reduces appetite signaling, and improves insulin sensitivity

Despite the challenges posed by the limited signal-to-noise ratio of fMRI in deep brain nuclei, advances in imaging sequences 82,83,84 , ultra-high field MRI 85,86,87 and optimized processing methods 88,89,90,91,92 will further enhance the feasibility of this approach