Figure 1 2.1 Overproduction of ROS One hallmark feature of IBD is the overproduction of ROS, which causes dysregulation of signal transduction, an inflammatory response, and DNA damage, all of which contribute to the progression and deterioration of the disease ( 2), nitric oxide (NO), hydroxyl radical (-0H), hydroperoxyl radical (O 2 H), hydrogen peroxide (H 2 O 2 ), and singlet oxygen ( 2.2 Damage to biomolecules ROS can damage various cell biomolecules, including lipids, proteins, and DNA
Reducing oxidative stress Oxidative stress from free radicals is a common contributor to acne and skin ageing
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