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Overall, our binding analysis and Th-T assays of Syn 1103 with various interactors tested suggest that random cellular proteins are sequestered within inclusions due to the promiscuous binding nature of Syn 1103 , rather than exerting any inhibitory effect on its aggregation

Beyond these direct neurological actions, KD may also help restore gut eubiosis, an effect of growing relevance given the expanding evidence implicating GI dysfunction in both the pathogenesis and progression of PD

Modeling approaches now incorporate the bioconcentration of both parent pesticides and their metabolites, improving risk assessment accuracy and highlighting the need for databases on plant-specific metabolic rates