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NMDA, N-Methyl-D-Aspartate

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By using either CRP funding or the new capacity now available under the 2012 SBIR reauthorization to provide a sequential Phase II, AF was able to provide additional funding of up to $2.25 million per project (see Figure 4-2)

The immune protection of embryo by kynurenines is further supported by the observations that with progressing pregnancy, IDO (indoleamine-2,3-dioxygenase, the enzyme initiating tryptophan catabolism) expression is up-regulated by inflammatory cytokines including its most potent stimulant, interferon gamma, and immunosuppressive kynurenines are generated [12]