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Thus, with such a background (i.e., useful modulation/control of the increased angiogenesis, elevated VEGF levels, upregulation of the egr-1 gene, enhanced NO and eNOS stimulation, and counteraction of increased free radical formation), stable gastric pentadecapeptide BPC 157 is working as a cytoprotective agent (and, therefore, with a highly postulated safety profile) (and not as a panacea effective for all conditions)

The panelists also discussed the current challenges surrounding immunosuppression, which is one of the barriers to clinical trial participation, and ongoing efforts to develop novel cell protection strategies

(March 2020)

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