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Proteomaps (www.proteomaps.net) based on RNA transcript data were drawn to visualise three levels of functional categories based on KEGG pathway analysis (www.genome.jp/kegg/) (29) Analysis of immune cell infiltration and the glandular microenvironment The cell type of each cluster (43 immune cells and 8 salivary glandular compositions) was identified using the CellMarker database and by aligning marker genes to known signature genes reported in previous studies (30)